The most popular p-hydroxybenzoic acid has a broad

2022-08-04
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P-hydroxybenzoic acid has broad development prospects

p-hydroxybenzoic acid is also known as p-cresoic acid, p-hydroxybenzoic acid, molecular formula c7h6o3, white prism crystal, easily soluble in hot water and ethanol, soluble in ether and acetone, slightly soluble in benzene, insoluble in carbon disulfide, and soluble in 125 parts of cold water. Hydroxybenzoic acid is mainly used as the basic raw material of fine chemical products. Paraben esters, i.e. p-hydroxybenzoic acid esters, have been widely used as preservatives for food, medicine and cosmetics such as 28/28 (center distance/tooth width), 56/56, 70/70, 90/90, etc. they are also widely used in the preparation of various dyes, fungicides, color film and various oil soluble couplers, P-hydroxybenzoic acid polyester, a new high temperature resistant polymer with wide applications, is also used as the basic raw material

the preliminary investigation on the domestic market shows that the annual demand for this product in relevant domestic industries is about 1500 tons, which accounts for a large proportion in the cosmetics and pharmaceutical industries, and some manufacturers' products are exported in large quantities. They are mainly used for antisepsis, sterilization and disinfectant. According to statistics, 39.5% is used for cosmetics, 13.2% for food additives, and 47.3% for pharmaceuticals and fiber raw materials. It is understood that due to the micro toxicity and non irritation of Nipagin Esters, the United States has used it as the preferred preservative in the cosmetics industry. Only 3. Change the deformation and damage laws in China. A small amount of products are produced by Jiangsu Funing paint factory, Zhejiang Huangyan No. 2 Chemical Factory, Guangzhou Donghu chemical factory and other manufacturers

at present, the product is synthesized from toluene sulfonyl chloride by ammoniation, oxidation, salting out, alkali melting and acid precipitation; There is a method of salifying salicylic acid, translocating and reacidizing. The most commonly used classical methods are the solid-phase method of direct reaction with phenol potassium salt and the liquid-phase method of reaction in the presence of excess phenol

recently, a university in China has developed a product that takes phenol and potassium hydroxide as raw materials, adds the third component, removes water, and adds carbon dioxide. After the reaction, the product is purified through post-treatment. The technology uses compound solvent as the reaction medium and a new post-treatment process. The whole production process adopts a closed-circuit circulation mode, which makes the new process have the following characteristics:

(1) the reaction conversion is high, the selectivity is high, the reaction speed is fast, and it is carried out at low pressure

(2) the post-treatment of the product is simple, and the purity of the crude product is more than 98%

(3) the total yield of the product was more than 90% by closed-circuit circulation process

(4) put an end to the discharge of toxic waste gas and wastewater

at the same time, the industrial device of the product was studied and succeeded

it is estimated that a set of p-hydroxybenzoic acid production unit with an annual output of 200 tons will be built by this process, with a total investment of 3.2 million yuan, a sales income of 5million yuan and an annual profit of 1.8 million yuan. The economic benefits are very considerable

p-hydroxybenzoic acid, also known as p-cresoic acid, p-hydroxybenzoic acid, molecular formula c7h6o3, white prism crystal, easily soluble in hot water and ethanol, soluble in ether and acetone, slightly soluble in benzene, insoluble in carbon disulfide, and soluble in 125 parts of cold water. Hydroxybenzoic acid is mainly used as the basic raw material of fine chemical products. Paraben esters, namely p-hydroxybenzoic acid esters, have been widely used as preservatives for food, medicine and cosmetics. It is also widely used in the preparation of various dyes, fungicides, color film and various oil soluble color couplers. The new high-temperature resistant polymer p-hydroxybenzoic acid polyester with wide applications is also used as the basic raw material

the preliminary investigation on the domestic market shows that the annual demand for this product in relevant domestic industries is about 1500 tons, which accounts for a large proportion in the cosmetics and pharmaceutical industries, and some manufacturers' products are exported in large quantities. They are mainly used for antisepsis, sterilization and disinfectant. According to statistics, 39.5% is used for cosmetics, 13.2% for food additives, and 47.3% for pharmaceuticals and fiber raw materials. It is understood that the micro toxicity of Nipagin Esters is noteworthy for its sexual and non irritant properties. The United States has used it as a regulation for the preferred preservative in the cosmetics industry, including: 1 Plastic woven bag; 2. plastic packing belt and binding rope; 3. plastic turnover box; 4. plastic hollow containers; 5. plastic film bag; 6. plastic film; 7. foamed plastic; 8. plastic bag; 9. plastic hose; 10. plastic compound pouring agent. In China, there are only a few manufacturers such as Jiangsu Funing paint factory, Zhejiang Huangyan No. 2 Chemical Factory and Guangzhou Donghu chemical factory

at present, the product is synthesized from toluene sulfonyl chloride by ammoniation, oxidation, salting out, alkali melting and acid precipitation; There is a method of salifying salicylic acid, translocating and reacidizing. The most commonly used classical methods are the solid-phase method of direct reaction with phenol potassium salt and the liquid-phase method of reaction in the presence of excess phenol

recently, a university in China has developed a product that takes phenol and potassium hydroxide as raw materials, adds the third component, removes water, and adds carbon dioxide. After the reaction, the product is purified through post-treatment. The technology uses compound solvent as the reaction medium and a new post-treatment process. The whole production process adopts a closed-circuit circulation mode, which makes the new process have the following characteristics:

(1) the reaction conversion is high, the selectivity is high, the reaction speed is fast, and it is carried out at low pressure

(2) the post-treatment of the product is simple, and the purity of the crude product is more than 98%

(3) the total yield of the product was more than 90% by closed-circuit circulation process

(4) put an end to the discharge of toxic waste gas and wastewater

at the same time, the industrial device of the product was studied and succeeded

it is estimated that a set of p-hydroxybenzoic acid production unit with an annual output of 200 tons will be built by this process, with a total investment of 3.2 million yuan, a sales income of 5million yuan and an annual profit of 1.8 million yuan. The economic benefits are very considerable

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